An amino acid, arginine, is a crucial block of proteins in the body. It plays several roles in maintaining overall health. The most famous work of arginine is related to nitric oxide. Nitric oxide helps blood vessels to relax and contributes to improving blood flow. Arginine supplements could support heart health and lower blood pressure. Collagen formation is also involved in arginine. For the repair and healing of wounds, arginine may aid the recovery process. Arginine is also important in the functioning of the immune system and hormone regulation. But today, we will focus on its function of dilating blood vessels. It is involved in men’s sexual health, especially struggle with impotence , erectile dysfunction.

What arginine do?
Why arginine can help men’s pride? Arginine acts similarly to sildenafil, Viagra. As a natural source of Viagra, it can regulate blood flow. When the brain is stimulated by nerves, nitric oxide is generated in the wall of blood vessels. Generated nitric oxide activated cGMP, a vasodilator, a substance that expands blood vessels, causing penis volume expansion. Viagra blocks the decomposition of this cGMP. But arginine stimulates cGMP secretion. The arginine helps to make nitric oxide more. Nitric oxide produced by arginine activates cGMP levels, then lead to increase blood flow to the genital organ. (NO > cGMP > Expansion)
Since this nitric oxide decreases with age, it is necessary to take arginine supplements. In research, you can see that the level of nitric oxide in the blood increased when arginine was consumed an hour before exercise (1). As nitric oxide in the blood increases, it affects blood flow in the penis, and of course, the duration of erection is longer.

Arginine in muscle
Arginine is effective in increasing muscle duration, stiffness, and endurance. It is necessary to compensate for the physical limitations depending on age. Arginine is also used as a supplement to the working out powder condition. Arginine is said to have been effective in improving metabolism while reducing fat mass and promoting muscle mass by promoting the development of brown fat tissue. Arginine supplements are good for physical activities to enhance exercise performance. The improved blood flow and nutrient delivery to muscles may contribute to better endurance and recovery.

Arginine food
Arginine is building block of muscle, so we can find it in the meat and proteins easily. Meat such as beef, pork, chicken, and turkey are good sources of arginine. Salmon and tuna with large muscle also are arginine-rich fish. Dairy products like milk, yogurt and cheese provide arginine.
Plant-originated foods have lots of arginine. Nuts like almonds, peanuts, walnuts, sunflower seeds, and pumpkin seeds are rich in arginine. Beans, lentils, and chickpeas contain a high amount of protein with arginine. And soybean and tofu are good sources. Whole grains and dark chocolate contain some, too. These foods contain arginine, so it is important to balance the diet for proper intake of arginine.

Arginine supplement
Taking enough arginine amount is often hard to achieve through natural food consumption. Because arginine is a component that is poorly absorbed and is easily pushed out of competition with other amino acids, it is difficult to expect an effect if consumed less than 3,000 mg. So it is recommended to take arginine as a nutritional supplement. The average person needs 3000 to 6000 mg of arginine every day for proper functions. If you are taking 6000 mg of arginine before working out or using muscle, the nitric oxide levels in the blood may increase significantly.

Cautions
It is generally considered a safe ingredient, but some scientists worry about excessive intake of arginine. For patients with cancer , in some cases, arginine is taken to improve fatigue and boost energy boost energy during treatment for people in chemotherapy.
However, arginine or its precursor, citrulline, may affect mTOR protein. Arginine may activate mTOR; the mTOR pathway is a central regulator of mammalian metabolism and physiology. Its important roles in the function of tissues, including the liver, muscle, adipose tissue, and the brain, is dysregulated in certain cancers.
Activating mTOR may increase the possibility of cancer induction increases. Because antioxidant action is not controlled in the process of cell replication. Arginine promotes NO secretion and synthesis, and new blood vessels that cause cancer may develop further. In fact, they are studying enzymes that block arginine as anticancer drugs. Ask your doctor or any other professional if you are in the course of treating certain types of cancers.
(mTOR protein activation > cell proliferation, autophagy system inhibition > cancer potential)

References
1) Stephen J Bailey 1, Paul G Winyard, Anni Vanhatalo, Jamie R Blackwell, Fred J DiMenna, Daryl P Wilkerson, Andrew M Jones. Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance. J Appl Physiol (1985). 2010 Nov;109(5):1394-403.

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